Diphenhydramine in ampoules
Diphenhydramine in ampoules effectthrough the central nervous system. The drug removes spasm in smooth muscles, eliminates and prevents allergic reaction, reduces capillary permeability. "Dimedrol" (injections) has a hypnotic, sedative, antiemetic effect.
The drug is characterized by good absorption, the ability to penetrate the blood-brain barrier (BBB).
Diphenhydramine in ampoules is used, as a rule, fortreatment of hay fever, urticaria, capillarotoxicosis (hemorrhagic vasculitis), serum sickness, acute iridocyclitis, dermatoses (itching), angioedema, vasomotor rhinitis, allergic conjunctivitis and other allergic diseases, including to alleviate symptoms in complications of taking medications, in particular, antibiotics.
Like other antihistamines, the medication is used to treat radiation sickness.
A relatively small activity is manifested by the drug "Dimedrol" (in ampoules) with bronchial asthma. In this case, it is prescribed in combination with ephedrine, theophylline and other medicines.
In some cases, "diphenhydramine" in ampoulesprescribe for peptic ulcer in the stomach, hyperacid gastritis. The drug, along with other blockers of H1 receptors, can be used for transfusion of blood-substituting fluids and blood, as well as using enzyme and other drugs in order to reduce adverse reactions.
"Dimedrol" is shown in air and seaillness, chorea, Meniere's syndrome, vomiting of pregnant women. The therapeutic effect of medication for these diseases and conditions is based on central cholinolytic and sedative effects. As a provocative agent, its salt with chlorotheophyllin (dimenhydrinate) is more effective than "Diphenhydramine".
The drug is also used as a hypnotic and sedative as alone or in combination with other similar drugs.
In anesthetic practice, the drug is used as a component of lytic mixtures.
"Diphenhydramine" in ampoules. Instructions
Assign the drug intramuscularly or intravenously.
Dosage for children from fourteen years of age and adults - one or three times a day for 1-5 ml, children up to fourteen years - 0.3-0.5 ml of 1% solution.
Contraindications for glaucomaclosed-angle, prostatic hyperplasia, hypersensitivity, peptic ulcer in the duodenum and stomach, epilepsy, neck stenosis in the bladder, children up to seven months.
In pregnancy, bronchial asthma and lactation, the use of "Diphenhydramine" is allowed by appointment and under the supervision of a doctor.
The use of the drug may cause sensationheart beat, lowering blood pressure, extrasystole, tachycardia. Patients in some cases noted dryness of the mucous membranes (throat and nasal cavity), stuffiness in the nose, a feeling of chest compression.
The use of "diphenhydramine" may causeimpaired coordination, dizziness, confusion, nervousness, agitation, tremor, cramps, irritability. Negative reactions are also vomiting, epigastric pain, diarrhea, visual impairment, thrombocytopenia, anaphylactic shock, photosensitization, increased sweating, and other manifestations.
When an overdose occurs CNS depression,dilated pupils, development of depression or arousal (in children). It is carried out in this state intravenous fluids of plasma substitution, if necessary, prescribe drugs that increase blood pressure. In case of an overdose, do not use analeptics and epinephrine.
"Diphenhydramine" in any dosage form is dispensed only by prescription.